It’s much more addictive from that perspective.”īollini expands on this point by adding that, “Unless we serve these medicines in the framework of giving these drugs first as a dissociative experience - which is to say the experience that you are not your mind, and second as a booster to give you the courage, to give you the hard work, to change your lifestyle, it’s very easy to get hooked into it. The thing with ketamine is that it really doesn’t have that. You are confronted with your shadow, the difficult part of yourself that you have to integrate. The hardship that comes with these natural compounds makes it so you don’t abuse them. When you take mushrooms or medicines that require more work, to face your fears, it’s not an easy experience, but then the lasting effects are way longer. ![]() “On the other hand, it’s kind of a shortcut, it’s not a quantum leap. From a clinical perspective, it’s also shorter in duration. It’s very straight to the point, giving the insights that can help you, and clear in the messaging compared to say, ayahuasca. ![]() On the light side, it’s a very easy compound to administer, less scary compared to some natural compounds. When ketamine became legal under the FDA, I had to start working with it to understand the substance,” she tells Truffle Report. ![]() “The context in which I gave that quote is because as a medicine woman I mostly work with natural entheogens. Our first step was to go back to Flor Bollini to ask her to expand on her position. In this series, Truffle Report decided to reach out to the psychedelic community, and some of those in our sphere who are the most knowledgeable on ketamine-assisted therapy to discuss the risks, and the safety protocols currently in place. While these practices are more often associated with natural entheogens, the lessons of the underground space, and of pioneering practitioners from many cultures and backgrounds who operated outside the law, can and should inform our decision making and our knowledge, if for no other reason than patients will suffer if they do not. It’s important to remember that this current interest, and the proliferation of new clinics, is also built on the shoulders of underground psychedelic therapy. Addiction and dependence take many forms, and can have many beginnings. None of these completely mitigate the potential for something to go wrong. More properly called ketamine-assisted psychotherapy, the practice involves considerable screening, as well as emotional and psychological preparation and physical safety precautions. There’s no question that a patient receiving ketamine therapy from a reputable practitioner is in for a very different experience than that of a recreational user. We thought this was a danger worth exploring. In a previous Truffle Report interview, Maria Florencia “Flor” Bollini, founder and director of psychedelic telehealth provider NANA heals, states that “if we’re not careful, we might see an epidemic of ketamine addiction soon.” ![]() While the research proving it belongs there is sound, caution is essential. Thanks to approvals for drugs like Spravato (esketamine), ketamine has moved from animal tranquilizer and party drug to find a home in our therapeutic toolbox. All of this feels much like a precursor to an impending wave of psychedelic therapy practices, promised by the results of clinical trials and the loosening of laws in places like Oregon and California. Ketamine nasal sprays, infusions, injections, and lozenges are being offered in clinics springing up all over North America, and beyond. While technically a dissociative anesthetic, the substance now finds itself at the centre of booming interest in psychedelic medicines.
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